December 14, 2025
RetroCast and SynthArena: building the infrastructure for the next breakthrough in chemistry
A breakdown of Procrustean Bed for AI-Driven Retrosynthesis: A Unified Framework for Reproducible Evaluation
a deep dive into how the metrics for ai chemical synthesis are broken, rewarding models for "solving" routes with impossible, hallucinatory chemistry. we present the data and the open-source tools to fix it.
researchMLretrosynthesisinfrastructureevals